For the diagnostic of total sperm DNA fragmentation of human and veterinary sperm, based on the Sperm Chromatin Dispersion (SCD) Assay (Fernández et al., J. Androl 24:59-66, 2003; Fertil Steril 84:833-842, 2005).
Sperm DNA fragmentation refers to the presence of breaks in the genetic material within sperm cells, which can negatively impact fertility, embryo development, and pregnancy outcomes. Assessing DNA fragmentation is important for understanding male infertility and selecting appropriate treatment strategies.